Biography
Edward Hipkiss
Degrees
M.S. in Biology, Shippensburg University, 2003
B.S. in Biology, York College of Pennsylvania, 2001
Courses Taught
- BIOL 1: Preparation Skills for Success in Biology and Life Sciences
- BIOL 11: Introductory Biology I
- BIOL 12: Introductory Biolology II
- BIOL 133: Genetics and Evolution of the Human Species
- BIOL 155: Introduction to the Biology of Aging
- BISC 1: Structure and Function of Organisms
- BISC 2: Genetics, Ecology, and Evolution
- BISC 4: Human Body: Form and Function
- BMB 1: The Science of Sickness
- MICRB 106: Elementary Microbiology
- MICRB 107: Elementary Microbiology Laboratory
Faculty Scholarly Activities
- Drake, C. G., Pardoll, D. M., Powell, J. D., Getnet, D., Hipkiss, E. L., Grosso, J. F., Patent, "COMPOSITIONS AND METHODS FOR MODULATING AN IMMUNE RESPONSE.", Sponsor/Agency Award number: 10329617. (application: June 9, 2016, approve: June 25, 2019).
- Jackson, C. M., Flies, D. B., Mosse, C. A., Parwani, A., Hipkiss, E. L. (Co-Author), & Drake, C. G. (2013). Strain-specific induction of experimental autoimmune prostatitis (EAP) in mice. Prostate, 73(6), 651-656
- Getnet, D., Grosso, J. F., Goldberg, M. V., Harris, T. J., Yen, H.-R., Bruno, T. C., Durham, N. M., Hipkiss, E. L., Pyle, K. J., Wada, S., Pan, F., Pardoll, D. M., & Drake, C. G. (2010). A role for the transcription factor Helios in human CD4(+)CD25(+) regulatory T cells. Molecular Immunology, 47(7-8), 1595-1600.
- Grosso, J. F., Goldberg, M. V., Getnet, D., Bruno, T. C., Yen, H.-R., Pyle, K. J., Hipkiss, E. L., Vignali, D. A.A., Pardoll, D. M., & Drake, C. G. (2009). Functionally Distinct LAG-3 and PD-1 Subsets on Activated and Chronically Stimulated CD8 T Cells. Journal of Immunology, 182, 6659-6669.
Research Interests
Tumor immunology and immunotherapies
Publications
Strain-specific induction of experimental autoimmune prostatitis (EAP) in mice., Prostate - May, 2013
A role for the transcription factor Helios in human CD4(+)CD25(+) regulatory T cells., Molecular Immunology - April (2nd Quarter/Spring), 2010
Naive tumor-specific CD4+ T cells differentiated in vivo eradicate established melanoma, Journal of Experimental Medicine - March 15, 2010
Functionally Distinct LAG-3 and PD-1 Subsets on Activated and Chronically Stimulated CD8 T Cells, Journal of Immunology - June 1, 2009
Cyclophosphamide Augments Antitumor Immunity: Studies in an Autochthonous Prostate Cancer Model, Cancer Research - May 15, 2009
Tumor Recognition and Self-Recognition Induce Distinct Transcriptional Profiles in Antigen-Specific CD4 T Cells, Journal of Immunology - April (2nd Quarter/Spring) 15, 2009
Radiotherapy augments the immune response to prostate cancer in a time-dependent manner, Prostate - September 1, 2008
LAG-3 regulates CD8+ T cell accumulation and effector function in murine self- and tumor-tolerance systems., Journal of Clinical Investigation - November, 2007
Cutting edge: An in vivo requirement for STAT3 signaling in TH17 development and TH17-dependent autoimmunity., Journal of Immunology - October (4th Quarter/Autumn) 1, 2007
Role of PD-1 and its ligand, B7-H1, in early fate decisions of CD8 T cells, Blood - July (3rd Quarter/Summer) 1, 2007
Androgen ablation mitigates tolerance to a prostate/prostate cancer-restricted antigen, Cancer Cell - March 7, 2005
Role of LAG-3 in Regulatory T Cells, Immunity - October (4th Quarter/Autumn), 2004
Bacteriolytic therapy can generate a potent immune response against experimental tumors, Proceedings of the National Academy of Sciences - October (4th Quarter/Autumn) 19, 2004
Education
MS, Biology, Shippensburg University
BS, Biology, York College of Pennsylvania