Linghao Zhong

Director of Academic Affairs, Academic Affairs
Chief Academic Officer, Academic Affairs
Professor, Chemistry
Faculty, Honors Program
315, Sci-Tech
Penn State Mont Alto | 1 Campus Drive | Mont Alto, PA 17237

EDUCATIO:
Ph.D., Chemistry, University of Rochester, 2003

SELECTED SCHOLAR ACTIVITIES:
Jiangbing Xu, Youzhi Feng, Nieves Barros, Linghao Zhong, Ruirui Chen, Xiangui Lin, Exploring the potential of microcalorimetry to study soil microbial metabolic diversity, , Journal of Thermal Analysis and Calorimetry, 2017, 2 1457-1465
Zhen Zhao, Vincent H. Crespi, James D. Kubicki, Daniel J. Cosgrove, Linghao Zhong, Molecular dynamics simulation study of xyloglucan adsorption on cellulose surfaces: effects of surface hydrophobicity and side-chain variation, Cellulose, 2014, 21, 1025-1039
Tuo Wang, Yong Bum Park, Marc A. Caporini, Melanie Rosay, Linghao Zhong, Daniel J. Cosgrove, and Mei Hong, Sensitivity-enhanced solid-state NMR detection of expansin's target in plant cell walls, PNAS, 2013, 110, 16444-16449
Zhen Zhao, Oleg Shklyaev, Abdolmajid Nili, Mohamed Naseer Ali Mohamed, James David Kubicki, Vincent H. Crespi, Linghao Zhong, Cellulose Microfibril Twist, Mechanics and Implication for Cellulose Biosynthesis, J. Phys. Chem. A, 2013, 117, 2580-2589
Linghao Zhong, Exposure of Hydrophobic Core in Human Prion Protein Pathogenic Mutant H187R, J. Biomol. Struct. Dyn., 2010, 28, 355-361
Linghao Zhong, James Matthews, Peter Hansen, Michael Crowley, Joseph Cleary, Ross Walker, Mark Nimlos, Charles Brooks III, William Adney, Michael Himmel, John Brady, Computational simulations of the Trichoderma reesei cellobiohydrolase I acting on microcrystalline cellulose Ib: the enzyme-substrate complex, Carbohydrate Research, 2009, 334, 1984-1992
Linghao Zhong, Xin Wen, Terry M. Rabinowitz, Brandy S. Russell, Elizabeth F. Karan, Kara L. Bren, Heme axial methionine fluxionality in Hydrogenobacter thermophilus cytochrome c552, PNAS, 2004, 101, 8637-8642

TEACHING:
CHEM 108: Problem Solving in Chemistry
CHEM 110: Chemical Principles I
CHEM 111: Experimental Chemistry I
CHEM 112: Chemical Principles II

STUDENT RESERCH PROJECTS:
- Water quality monitoring in Antietam Creek
- Biodiesel production
- Roadside wind energy

Closing the gap between climate regulation and food security with nano iron oxides, Nature Sustainability - June 1, 2024
Collaborators: Yongjie Yu, Author; Youzhi Feng, Author; Yingliang Yu, Author; Lihong Xue, Author; Linzhang Yang, Author; Manuel Delgado-Baquerizo, Author; Shiying He, Author

Editorial: Microbial Interactions With Nanomaterials in the Environment and Their Application, FRONTIERS IN MICROBIOLOGY - 2022
Collaborators: Fayuan Wang, Author; Yucheng Wu, Author; Shiying He, Author

Microbial Community Composition and Activity in Saline Soils of Coastal Agro-Ecosystems, MICROORGANISMS - 2022
Collaborators: Yang Dong, Author; Jianwei Zhang, Author; Ruirui Chen, Author; Xiangui Lin, Author; Youzhi Feng, Author

Balanced stochastic versus deterministic assembly processes benefit diverse yet uneven ecosystem functions in representative agroecosystems, ENVIRONMENTAL MICROBIOLOGY - 2021
Collaborators: Wenjing Liu, Author; Emily Graham, Author; Yang Dong, Author; Jianwei Zhang, Author; Chongwen Qiu, Author; Ruirui Chen, Author; Xiangui Lin, Author; Youzhi Feng, Author

Balanced stochastic vs. deterministic assembly processes benefit multifunctionality for agroecosystem sustainability, Environmental Micorbiology - November 17, 2020
Collaborators: Wenjing Liu; Yang Dong; Jianwei Zhang; Chongwen Qiu; Ruirui Chen; Xiangui Lin; Youzhi Feng

Long-Term Stochasticity Combines With Short-Term Variability in Assembly Processes to Underlie Rice Paddy Sustainability, Frontiers in Microbiology - May 15, 2020
Collaborators: Wenjing Liu; Emily Graham; Jianwen Zhang; Shijie Li; Xiangui Lin; Youzhi Feng

Dynamic microbial assembly processes correspond to soil fertility in sustainable paddy agroecosystems, Functional Ecology - February 28, 2020
Collaborators: Wenjin Liu, Author; Emily Graham; Jianwei Zhang; Weitao Li; Zhongpei Li; Xiangui Lin; Youzhi Feng

Balanced Fertilization Decreases Environmental Filtering on Soil Bacterial Community Assemblage in North China, FRONTIERS IN MICROBIOLOGY - 2017
Collaborators: Youzhi Feng, Author; Zhiying Guo, Author; Fei Zhao, Author; Jiabao Zhang, Author; Xiangui Lin, Author

Bioremediation of Wastewater by Iron Oxide-Biochar Nanocomposites Loaded with Photosynthetic Bacteria, FRONTIERS IN MICROBIOLOGY - 2017
Collaborators: Shiying He, Author; Jingjing Duan, Author; Yanfang Feng, Author; Bei Yang, Author; Linzhang Yang, Author

Exploring the potential of microcalorimetry to study soil microbial metabolic diversity, JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY - 2017
Collaborators: Jiangbing Xu, Author; Youzhi Feng, Author; Nieves Barros, Author; Ruirui Chen, Author; Xiangui Lin, Author

Fertilization decreases compositional variation of paddy bacterial community across geographical gradient, SOIL BIOLOGY & BIOCHEMISTRY - 2017
Collaborators: Ruirui Chen, Author; Zhongwang Jing, Author; Zhiying Guo, Author; Zhongpei Li, Author; Xiangui Lin, Author; Youzhi Feng, Author

Geographical Distribution of Methanogenic Archaea in Nine Representative Paddy Soils in China, FRONTIERS IN MICROBIOLOGY - 2016
Collaborators: Qianhui Zu, Author; Ye Deng, Author; Yu Shi, Author; Baozhan Wang, Author; Zhongjun Jia, Author; Xiangui Lin, Author; Youzhi Feng, Author

Hydrogen-Bonding Network and OH Stretch Vibration of Cellulose: Comparison of Computational Modeling with Polarized IR and SFG Spectra, J. Phys. Chem. B - 2015
Collaborators: Christopher Lee; James Kubicki; Bingxin Fan; Michael Jarvis; Seong Kim

Insight into structural rearrangements and interdomain interactions related to electron transfer between flavin mononucleotide and heme in nitric oxide synthase: A molecular dynamics study., Journal of Inorganic Biochemistry - August 7, 2015
Collaborators: Y Sheng, Author; D Guo, Author; G Lau, Author; C Feng, Author

Molecular dynamics simulation study of xyloglucan adsorption on cellulose surfaces: effects of surface hydrophobicity and side-chain variation, Cellulose - April, 2014
Collaborators: Zhen Zhao, Primary Author; Vincent Crespi, Co-Author; James Kubicki, Co-Author; Daniel Cosgrove, Co-Author

Sensitivity-enhanced solid-state NMR detection of expansin’s target in plant cell walls, PNAS - October, 2013
Collaborators: Tuo Wang; Yong Bum Park; Marc Caporini; Melanie Rosay; Daniel Cosgrove; Hong Mei

Quantum mechanical calculations on cellulose–water interactions: structures, energetics, vibrational frequencies and NMR chemical shifts for surfaces of Iα and Iβ cellulose, Cellulose - August 23, 2013
Collaborators: James Kubicki, Primary Author; Heath Watts, Author; Zhen Zhao, Co-Author

Probing the interaction between cellulose and cellulase with a nanomechanical sensor, Book title "Cellulose" - July, 2013
Collaborators: Jun Xi, Primary Author; Wenjian Du, Co-Author

Cellulose Microfibril Twist, Mechanics and Implication for Cellulose Biosynthesis, J. Phys. Chem. A - February 18, 2013
Collaborators: Zhen Zhao, Author; Oleg Shklyaev, Co-Author; Abdolmajid Nili, Co-Author; Mohamed Mohamed; James Kubicki; Vincent Crespi

Dynamic Multibody Protein Interactions Suggest Versatile Pathways for Copper Trafficking, J. Am. Chem. Soc. - May 11, 2012
Collaborators: Aaron Keller; Jaime Benitez; Derek Klarin; Matthew Goldfogel; Feng Yang; Tai-Yen Chen; Peng Chen

Sugar-binding sites on the surface of the carbohydrate-binding module of CBH I from Trichoderma reesei, Carbohydrate Research - May, 2011
Collaborators: Letizia Tavagnacco; Philip Mason; Udo Schnupf; Felicia Pitici; Michael Himmel; Michael Crowley, Co-Author; Attilio Cesaro; John Brady

Exposure of Hydrophobic Core in Human Prion Protein Pathogenic Mutant H187R , J. Biomol. Struct. Dyn. - December, 2010

Computational simulations of the Trichoderma reesei cellobiohydrolase I acting on microcrystalline cellulose Iβ: the enzyme–substrate complex , Carbohydrate Research - October, 2009
Collaborators: James Matthews, Author; Peter Hanson; Michael Crowley; Ross Walker; Mark Nimlos; Charles Brooks III; William Adney; Michael Himmel; John Brady

Investigation of the effect of glycosylation on human prion protein by molecular dynamics, J. Biomol. Struct. Dyn. - April, 2009
Collaborator: Jimin Xie

Interactions of the complete cellobiohydrolase I from Trichodera reesei with microcrystalline cellulose Iβ, Cellulose - April, 2008
Collaborators: James Matthews; Michael Crowley; Tauna Rignail; Cesar Talon; Joseph Cleary; Ross Walker; Giridhar Chukkapalli; Clare McCabe; Mark Nimlos; Charles Brooks; Michael Himmel; John Brady

Molecular modeling suggests induced fit of Family I carbohydrate-binding modules with a broken-chain cellulose surface., Protein engineering, design & selection : PEDS - April 1, 2007
Collaborators: M Nimlos; J Matthews; M Crowley; Ronald Walker; G Chukkapalli; J Brady; W Adney; J Cleary; M Himmel

Ph D, Chemistry, University of Rochester

BS, Chemistry, Nanjing University